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Invitrogen
Cytokeratin 81/86 Polyclonal Antibody
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Cytokeratin 81/86 Antibody (PA5-104293) in IHC (P)
Immunohistochemistry analysis of Cytokeratin 81/86 in mouse testis tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with Cytokeratin 81/86 polyclonal antibody (Product # PA5-104293) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-104293
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human KRT86(Accession O43790), corresponding to amino acid residues V261-H311.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total KRT81/86.
靶标信息
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ghHb1; ghHKb1; Hair keratin K2.11; Hair keratin K2.9; hard keratin, type II, 1; hard keratin, type II, 6; K81; K86; keratin 81, type II; keratin 86, type II; keratin complex 2, basic, gene 10; keratin complex 2, basic, gene 19; keratin protein HB6; Keratin, hair, basic, 1; keratin, hair, basic, 6 (monilethrix); Keratin, type II cuticular Hb1; Keratin, type II cuticular Hb6; Keratin-81; Keratin-86; krt81; Metastatic lymph node 137 gene protein; MLN 137; Type II hair keratin Hb1; Type II hair keratin Hb6; Type-II keratin Kb21; Type-II keratin Kb26
基因别名: 5430421N21Rik; AA589625; AI325212; ghHkb1; Hb-1; HB1; HB6; hHAKB2-1; K86; Khb4; Krt2-10; Krt2-11; Krt2-19; KRT81; KRT86; KRTHB1; KRTHB6; MHb4; MLN137; MNX
UniProt ID: (Human) Q14533, (Human) O43790, (Mouse) Q9ERE2, (Mouse) P97861
Entrez Gene ID: (Human) 3887, (Human) 3892, (Mouse) 64818, (Mouse) 16679
