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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Cytokeratin Pan Type II Antibodies

          NeoBiotechnologies

          Cytokeratin, Basic (Type II or HMW) Recombinant Rabbit Monoclonal Antibody (KRTH, 1576R)

          查看其他32个Cytokeratin Pan Type II抗体

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          Cite Cytokeratin, Basic (Type II or HMW) Recombinant Rabbit Monoclonal Antibody (KRTH, 1576R)

          • 抗体检测数据 (3)
          Cytokeratin, Basic (Type II or HMW) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          Cytokeratin, Basic (Type II or HMW) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          图: 1 / 3

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          Cytokeratin, Basic (Type II or HMW) Antibody (RBM22-1576-P1) in IHC (P)

          Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human skin using Cytokeratin, Basic (Type II or HMW) Recombinant Monoclonal Antibody (Product # RBM22-1576-P1). {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
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          Cytokeratin, Basic (Type II or HMW) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Cytokeratin, Basic (Type II or HMW) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Cytokeratin, Basic (Type II or HMW) Antibody in SDS-PAGE (SDS-PAGE)
          Cytokeratin, Basic (Type II or HMW) Recombinant Rabbit Monoclonal Antibody (KRTH, 1576R)

          产品信息

          RBM22-1576-P1

          应用
          建议稀释比
          已发表文章

          免疫组化(石蜡) (IHC (P))

          0.25-0.5 µg/mL
          -
          产品规格

          种属反应

          Dog, Human

          宿主/亚型

          Rabbit / IgG

          Expression System

          HEK293 cells

          分类

          Recombinant Monoclonal

          类型

          Antibody

          克隆号

          KRTH, 1576R

          抗原

          Recombinant full-length human KRT76 protein
          查看免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          200 µg/mL

          纯化类型

          Protein A/G

          保存液

          PBS, pH 7.4, with 0.05% BSA

          内含物

          0.05% sodium azide

          保存条件

          4°C

          运输条件

          Ambient (domestic); Wet ice (international)

          产品详细信息

          This antibody is expected to show broad species reactivity.

          Immunohistochemistry (PFA fixed): incubate antibody for 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.

          靶标信息

          Cytokeratin pan is part of a subfamily of intermediate filament proteins that are characterized by remarkable biochemical diversity, and represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight between 40 kDa- 68 kDa, and an isoelectric pH between 4.9-7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. The composition of cytokeratin pairs vary with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          引用该产品

          生物信息学

          蛋白别名: 58 kDa cytokeratin; 65 kDa cytokeratin; 67 kDa cytokeratin; CK-1; CK-2e; CK-2P; CK-3; CK-4; CK-5; CK-6A; CK-6D; CK-7; CK-72; CK-8; cytokeratin 1; cytokeratin 2; cytokeratin 3; cytokeratin 4; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; cytokeratin 7; Cytokeratin-1; Cytokeratin-2e; Cytokeratin-2P; Cytokeratin-3; Cytokeratin-4; Cytokeratin-5; Cytokeratin-6A; cytokeratin-6C; Cytokeratin-6D; cytokeratin-6E; Cytokeratin-7; Cytokeratin-72; Cytokeratin-8; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; epidermolytic hyperkeratosis 1; epithelial keratin 1; epithelial keratin 2e; Epithelial keratin-1; Epithelial keratin-2e; Hair alpha protein; K1; K2e; K2P; K3; K4; K5; K6A; K7; K72; K76; K8; kamp-keratin derived antimicrobial peptide; KDAMP; keratin 1 (epidermolytic hyperkeratosis); keratin 1, type II; keratin 2, type II; keratin 2A (epidermal ichthyosis bullosa of Siemens); keratin 2p; keratin 3, type II; keratin 4, type II; keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin 6, inner root sheath, 2; keratin 6A, , type II; keratin 6A, type II; keratin 7, type II; keratin 72, type II; keratin 76, type II; keratin 8, type II; keratin K6h; keratin protein K6irs; keratin, 55K type II cytoskeletal; keratin, epidermal type II, K6A; keratin, simple epithelial type I, K7; Keratin, type II cytoskeletal 1; Keratin, type II cytoskeletal 2 epidermal; Keratin, type II cytoskeletal 2 oral; Keratin, type II cytoskeletal 3; Keratin, type II cytoskeletal 4; Keratin, type II cytoskeletal 5; Keratin, type II cytoskeletal 6A; Keratin, type II cytoskeletal 7; Keratin, type II cytoskeletal 72; Keratin, type II cytoskeletal 8; Keratin-1; Keratin-2 epidermis; Keratin-2e; Keratin-3; Keratin-4; Keratin-5; Keratin-6A; keratin-6C; Keratin-7; Keratin-72; Keratin-76; Keratin-8; masticatory epithelia keratin 2p; MGC116967; MGC116968; pan keratin; Sarcolectin; Type II inner root sheath-specific keratin-K6irs2; type II mesothelial keratin K7; Type-II keratin Kb1; type-II keratin Kb12; Type-II keratin Kb2; Type-II keratin Kb3; Type-II keratin Kb35; Type-II keratin Kb4; Type-II keratin Kb5; Type-II keratin Kb6; Type-II keratin Kb7; Type-II keratin Kb8; Type-II keratin Kb9

          查看更多 收起

          基因别名: CARD2; CK-2e; CK-4; CK-6C; CK-6E; CK-8; CK1; CK3; CK4; CK5; CK6A; CK6C; CK6D; CK7; CK8; CYK4; CYK8; DDD; DDD1; EBS2; EHK; EHK1; EPPK; HUMCYT2A; K1; K2C7; K2C8; K2E; K3; K4; K5; K6A; K6C; K6D; K6irs; K6IRS2; K7; K8; KB35; KER1; KO; KRT1; KRT1A; KRT2; KRT2A; KRT2B; KRT2E; KRT2P; KRT3; KRT4; KRT5; KRT5A; KRT6; KRT6A; KRT6C; KRT6D; KRT6IRS2; KRT7; KRT72; KRT76; KRT8; KRTA; KRTE; NEPPK; PC3; SCL; WSN1

          查看更多 收起

          UniProt ID: (Dog) Q6EIY9, (Human) P86104, (Human) P35908, (Human) P12035, (Human) P19013, (Human) P13647, (Human) P02538, (Human) P08729, (Human) Q14CN4, (Human) Q01546, (Human) P05787

          查看更多 收起

          Entrez Gene ID: (Dog) 444857, (Human) 3848, (Human) 3849, (Dog) 444850, (Human) 3850, (Dog) 100683401, (Human) 3851, (Dog) 100682832, (Dog) 100687760, (Human) 3852, (Dog) 486523, (Human) 3853, (Dog) 477602, (Human) 3855, (Dog) 486520, (Human) 140807, (Dog) 486518, (Human) 51350, (Dog) 486513, (Human) 3856

          查看更多 收起

          功能
          protein heterodimerization activity receptor activity structural molecule activity protein binding carbohydrate binding structural constituent of cytoskeleton scaffold protein binding molecular_function protein complex binding
          参与通路
          epithelial cell differentiation intermediate filament cytoskeleton organization cytoskeleton organization negative regulation of epithelial cell proliferation protein heterotetramerization complement activation, lectin pathway retina homeostasis response to oxidative stress fibrinolysis regulation of angiogenesis negative regulation of inflammatory response establishment of skin barrier epidermis development keratinization keratinocyte activation keratinocyte proliferation keratinocyte migration positive regulation of epidermis development sebaceous gland development viral process tumor necrosis factor-mediated signaling pathway sarcomere organization response to hydrostatic pressure response to other organism cell differentiation involved in embryonic placenta development extrinsic apoptotic signaling pathway hepatocyte apoptotic process biological_process hemidesmosome assembly
          It has to be done as per old AB suggested Products section.
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          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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