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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Cytokeratin Pan Type I/II Antibodies

          NeoBiotechnologies

          Cytokeratin, Multi (Epithelial Marker) Monoclonal Antibody (C11)

          查看其他51个Cytokeratin Pan Type I/II抗体

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          说明书
          实验方案
          问题与答案
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          Cite Cytokeratin, Multi (Epithelial Marker) Monoclonal Antibody (C11)

          • 抗体检测数据 (5)
          Cytokeratin, Multi (Epithelial Marker) Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          Cytokeratin, Multi (Epithelial Marker) Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          图: 1 / 5

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          Cytokeratin, Multi (Epithelial Marker) Antibody (MSM1-393-P0) in ICC/IF

          Immunofluorescence analysis of HeLa cells labeling Multi Cytokeratin with Multi Cytokeratin Mouse Monoclonal Antibody (C11) conjugated with CF640R(Green). The nuclear counterstain is DAPI (Blue). {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
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          Cytokeratin, Multi (Epithelial Marker) Antibody in Immunocytochemistry (ICC/IF)
          Cytokeratin, Multi (Epithelial Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Cytokeratin, Multi (Epithelial Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Cytokeratin, Multi (Epithelial Marker) Antibody in Flow Cytometry (Flow)
          Cytokeratin, Multi (Epithelial Marker) Antibody in SDS-PAGE (SDS-PAGE)
          Cytokeratin, Multi (Epithelial Marker) Monoclonal Antibody (C11)

          产品信息

          MSM1-393-P0

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          1-2 µg/mL
          -

          免疫组化(石蜡) (IHC (P))

          Assay-dependent
          -

          免疫组织化学(多聚甲醛固定) (IHC (PFA))

          1-2 µg/mL
          -

          免疫细胞化学 (ICC/IF)

          1-4 µg/mL
          -

          流式细胞分析 (Flow)

          1-2 µg/10^6 cells
          -
          产品规格

          种属反应

          Amphibian, Bovine, Guinea pig, Goat, Human, Mouse, Non-human primate, Pig, Rat

          宿主/亚型

          Mouse / IgG1, kappa

          分类

          Monoclonal

          类型

          Antibody

          克隆号

          C11

          抗原

          Keratin-enriched preparation from cultured human A431
          查看免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          200 µg/mL

          纯化类型

          Protein A/G

          保存液

          PBS, pH 7.4, with 0.05% BSA

          内含物

          0.05% sodium azide

          保存条件

          4°C, do not freeze

          运输条件

          Ambient (domestic); Wet ice (international)

          靶标信息

          Cytokeratin pan is part of a subfamily of intermediate filament proteins that are characterized by remarkable biochemical diversity, and represented in human epithelial tissues by at least 20 different polypeptides. Cytokeratins range in molecular weight between 40 kDa- 68 kDa, and an isoelectric pH between 4.9-7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. The composition of cytokeratin pairs vary with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

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          引用该产品

          生物信息学

          蛋白别名: 39.1; 40-kDa keratin intermediate filament; 47 kDa cytokeratin; 56 kDa cytokeratin; 57kd keratin; 57kDa keratin; 58 kDa cytokeratin; 60-kDa keratin; 65 kDa cytokeratin; 67 kDa cytokeratin; Cell proliferation-inducing gene 46 protein; CK 2e; CK-1; CK-10; CK-13; CK-14; CK-15; CK-16; CK-17; CK-18; CK-19; CK-1B; CK-2e; CK-2P; CK-3; CK-4; CK-5; CK-6A; CK-6D; CK-7; CK-8; cytokeratin 1; cytokeratin 10; cytokeratin 13; cytokeratin 14; cytokeratin 15; cytokeratin 16; cytokeratin 18; cytokeratin 19; cytokeratin 2; cytokeratin 3; cytokeratin 4; cytokeratin 5; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; Cytokeratin 7; cytokeratin 8; Cytokeratin endo A; Cytokeratin endo B; cytokeratin type II, component Ia; cytokeratin type II, component Ib/c; cytokeratin type II, component III; Cytokeratin VIB; cytokeratin VII; Cytokeratin-1; Cytokeratin-10; Cytokeratin-13; Cytokeratin-14; Cytokeratin-15; Cytokeratin-16; Cytokeratin-17; Cytokeratin-18; Cytokeratin-19; Cytokeratin-1B; Cytokeratin-2e; Cytokeratin-2P; Cytokeratin-3; Cytokeratin-4; Cytokeratin-5; Cytokeratin-6A; Cytokeratin-6B; cytokeratin-6C; Cytokeratin-6D; cytokeratin-6E; Cytokeratin-7; Cytokeratin-8; Cytokeratin-A; Cytoskeletal 57 kDa keratin; embryonic type II keratin 1; Embryonic type II keratin-1; Endo B; epidermal keratin 10; epidermal keratin VII; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; epidermolysis bullosa simplex, Dowling-Meara, Koebner; epidermolytic hyperkeratosis 1; epidermolytic hyperkeratosis; keratosis palmaris et plantaris; Epithelial keratin-2e; focal non-epidermolytic palmoplantar keratoderma; Hair alpha protein; HMWCK; intermediate filament protein; K1; K10; K13; K14; K15; K16; K17; K18; K19; K1B; K2e; K2P; K3; K4; K5; K6A; K7; K76; K77; K8; kamp-keratin derived antimicrobial peptide; KDAMP; KERA; keratin 1, type II; keratin 10; keratin 10 (epidermolytic hyperkeratosis); keratin 10, type I; keratin 13, type I; keratin 14; keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner); keratin 14, type I; keratin 15; keratin 15, type I; keratin 16, type I; keratin 17; keratin 17, type I; keratin 18, type I; keratin 19; keratin 19, type I; Keratin 1B; keratin 2 (epidermal ichthyosis bullosa of Siemens); keratin 2 epidermis; keratin 2, type II; keratin 2A; keratin 2p; keratin 3, type II; keratin 4, type II; keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin 6 alpha; keratin 6A, , type II; keratin 6A, type II; keratin 6B; keratin 7, type II; keratin 76, type II; keratin 77; keratin 77, type II; keratin 8, type II; keratin 86; keratin complex 1, acidic, gene 10; keratin complex 1, acidic, gene 13; keratin complex 1, acidic, gene 14; keratin complex 1, acidic, gene 15; keratin complex 1, acidic, gene 16; keratin complex 1, acidic, gene 17; keratin complex 1, acidic, gene 18; keratin complex 1, acidic, gene 19; keratin complex 2, basic, gene 1; keratin complex 2, basic, gene 17; keratin complex 2, basic, gene 39; keratin complex 2, basic, gene 4; keratin complex 2, basic, gene 5; keratin complex 2, basic, gene 6a; keratin complex 2, basic, gene 6c; keratin complex 2, basic, gene 7; keratin complex 2, basic, gene 8; keratin complex 2, gene 17; keratin complex 2, gene 6a; Keratin D; keratin intermediate filament 16a; keratin intermediate filament 16b; keratin IV; keratin K6h; Keratin type II cytoskeletal 5; keratin, 55K type II cytoskeletal; keratin, epidermal type II, K6A; keratin, simple epithelial type I, K7; Keratin, type I cytoskeletal 10; Keratin, type I cytoskeletal 13; Keratin, type I cytoskeletal 14; Keratin, type I cytoskeletal 15; Keratin, type I cytoskeletal 16; Keratin, type I cytoskeletal 17; Keratin, type I cytoskeletal 18; Keratin, type I cytoskeletal 19; Keratin, type I cytoskeletal 59 kDa; keratin, type I, 40-kd; Keratin, type II cytoskeletal 1; Keratin, type II cytoskeletal 1b; Keratin, type II cytoskeletal 2 epidermal; Keratin, type II cytoskeletal 2 oral; Keratin, type II cytoskeletal 3; Keratin, type II cytoskeletal 4; Keratin, type II cytoskeletal 5; keratin, type II cytoskeletal 59 kDa, component IV; keratin, type II cytoskeletal 60 kDa, component III; Keratin, type II cytoskeletal 6A; Keratin, type II cytoskeletal 7; Keratin, type II cytoskeletal 8; Keratin-1; Keratin-10; Keratin-13; Keratin-14; Keratin-15; keratin-15, basic; keratin-15, beta; Keratin-16; Keratin-17; Keratin-18; Keratin-19; Keratin-2 epidermis; Keratin-2e; Keratin-3; Keratin-4; Keratin-5; Keratin-6-alpha; Keratin-6A; keratin-6C; Keratin-7; Keratin-76; Keratin-77; Keratin-8; krt1 {ECO:0000250|UniProtKB:P04264}; krt10 {ECO:0000250|UniProtKB:P13645}; krt13 {ECO:0000250|UniProtKB:P13646}; krt15 {ECO:0000250|UniProtKB:P19012}; krt17 {ECO:0000250|UniProtKB:Q04695}; krt18 {ECO:0000250|UniProtKB:P05783}; KRT1B; krt2; krt2 {ECO:0000250|UniProtKB:P35908}; krt4 {ECO:0000250|UniProtKB:P19013}; krt5; krt7; krt7 {ECO:0000250|UniProtKB:P08729}; krt76; mK6-alpha; Pan CK; pan Cytokeratin; pan keratin; pankeratin; Sarcolectin; suprabasal cytokeratin 10; tuftelin interacting protein 8; type I cytoskeletal 15; type I keratin KA10; Type I keratin Ka13; Type I keratin Ka14; Type I keratin Ka15; type I keratin KA16; Type I keratin Ka17; Type I keratin Ka19; type II cytokeratin A (no.8); type II cytoskeletal 1b; type II keratin Kb1; type II keratin Kb2; type II keratin Kb39; type II keratin Kb4; type II keratin Kb7; type II keratin Kb9; type II mesothelial keratin K7; type-II intermediate filament protein; Type-II keratin Kb1; type-II keratin Kb12; Type-II keratin Kb2; Type-II keratin Kb3; Type-II Keratin Kb39; Type-II keratin Kb4; Type-II keratin Kb5; Type-II keratin Kb6; Type-II keratin Kb7; Type-II keratin Kb8; Type-II keratin Kb9; unnamed protein product

          查看更多 收起

          基因别名: 2310001L23Rik; 2310016L08Rik; 3300001P10Rik; 39.1; 4732484G22Rik; AA960620; AI324768; AI528832; AI626930; AI663979; AL022697; AU019895; AW108092; AW146334; BB005427; BCIE; BIE; CARD2; CK-17; CK-18; CK-2e; CK-4; CK-6C; CK-6E; CK-8; CK1; CK10; CK13; CK14; CK15; CK16; CK18; CK19; CK3; CK4; CK5; CK6A; CK6C; CK6D; CK7; CK8; CYK18; CYK4; CYK8; CYKER; D130054E02Rik; D15Wsu77e; DDD; DDD1; EBS2; EBS3; EBS4; EHK; EHK1; EndoA; EndoC; EPPK; FNEPPK; HUMCYT2A; K1; K10; K13; K14; K15; K16; K17; K18; K19; K1B; K1C1; K1CO; K1CP; K1CS; K1emb; K2C7; K2C8; K2e; K3; K4; K5; K6A; K6C; K6D; K7; K8; Ka10; Ka13; Ka14; Ka15; Ka16; Ka17; Ka19; Kb1; Kb2; Kb39; Kb4; Kb7; Kb9; Ker2; Kerd; KERIA; KERIB; KO; KPP; Krt-1.10; Krt-1.13; Krt-1.14; Krt-1.19; Krt-2.1; Krt-2.4; Krt-2.8; KRT1; Krt1-10; Krt1-13; Krt1-14; Krt1-15; Krt1-16; Krt1-17; Krt1-18; Krt1-19; KRT10; KRT13; KRT14; KRT15; KRT16; KRT16A; KRT17; KRT18; KRT19; KRT1A; KRT1B; KRT2; Krt2-1; Krt2-17; Krt2-2; Krt2-4; Krt2-5; Krt2-6; Krt2-6a; Krt2-6c; Krt2-7; KRT2-8; Krt239; KRT2A; KRT2B; KRT2E; KRT2P; KRT3; KRT4; KRT5; KRT5A; Krt6; KRT6A; Krt6b; KRT6C; KRT6D; KRT7; KRT76; KRT77; KRT8; Krt86; KRTA; KRTB; KRTE; mK1b; mK6[a]; MK6a; NEPPK; NFJ; PC; PC1; PC2; PC3; PCHC1; PIG46; Sak57; SCL; Tfip8; WSN1; WSN2

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          UniProt ID: (Human) P86104, (Bovine) P06394, (Human) P13645, (Human) P13646, (Human) P02533, (Human) P19012, (Human) P08779, (Bovine) A1L595, (Human) Q04695, (Human) P05783, (Bovine) P08728, (Human) P08727, (Human) P35908, (Human) P12035, (Human) P19013, (Human) P13647, (Bovine) Q5XQN5, (Human) P02538, (Bovine) Q29S21, (Human) P08729, (Human) Q01546, (Human) Q7Z794, (Bovine) P05786, (Human) P05787, (Mouse) P04104, (Rat) Q6IMF3, (Mouse) P02535, (Mouse) Q6PAI1, (Rat) Q6IFV4, (Mouse) Q61781, (Rat) Q6IFV1, (Mouse) Q61414, (Rat) Q6IFV3, (Mouse) Q9Z2K1, (Mouse) Q9QWL7, (Rat) Q6IFU8, (Mouse) P05784, (Rat) Q5BJY9, (Mouse) P19001, (Rat) Q63279, (Mouse) Q3TTY5, (Rat) Q6IG02, (Rat) Q6IG00, (Mouse) P07744, (Rat) Q6P6Q2, (Mouse) Q922U2, (Mouse) P50446, (Rat) Q6IG12, (Mouse) Q9DCV7, (Mouse) Q3UV17, (Mouse) Q6IFZ6, (Rat) Q6IG01, (Rat) Q10758, (Mouse) P11679

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          Entrez Gene ID: (Pig) 100049664, (Goat) 102175951, (Human) 3848, (Bovine) 281888, (Goat) 102168294, (Pig) 100519971, (Human) 3858, (Human) 3860, (Goat) 102178106, (Human) 3861, (Bovine) 404111, (Pig) 100515506, (Bovine) 507464, (Human) 3866, (Human) 3868, (Bovine) 281889, (Human) 3872, (Human) 3875, (Bovine) 506480, (Pig) 100126286, (Goat) 102181566, (Bovine) 514812, (Pig) 100515339, (Human) 3880, (Goat) 106501743, (Pig) 100049665, (Human) 3849, (Goat) 102176227, (Human) 3850, (Bovine) 407188, (Pig) 100157304, (Goat) 102182381, (Bovine) 527819, (Human) 3851, (Goat) 102183210, (Pig) 100157675, (Human) 3852, (Goat) 102175207, (Pig) 100511564, (Bovine) 281268, (Pig) 102164968, (Goat) 102174931, (Human) 3853, (Bovine) 614456, (Bovine) 535697, (Goat) 102184596, (Human) 3855, (Human) 51350, (Bovine) 407189, (Goat) 102175675, (Pig) 100156059, (Human) 374454, (Pig) 100152077, (Bovine) 281269, (Human) 3856, (Goat) 102182762, (Guinea pig) 100714242, (Mouse) 16678, (Rat) 300250, (Mouse) 16661, (Rat) 450225, (Mouse) 16663, (Guinea pig) 100713183, (Rat) 287699, (Mouse) 16664, (Rat) 287701, (Mouse) 16665, (Rat) 287700, (Rat) 303530, (Mouse) 16666, (Mouse) 16667, (Rat) 287702, (Guinea pig) 100735962, (Mouse) 16668, (Rat) 294853, (Mouse) 16669, (Rat) 360626, (Guinea pig) 100714514, (Mouse) 16681, (Rat) 406228, (Guinea pig) 100713688, (Guinea pig) 100729006, (Rat) 315323, (Mouse) 16682, (Guinea pig) 100715346, (Rat) 369017, (Mouse) 110308, (Guinea pig) 100715629, (Mouse) 16687, (Rat) 300242, (Guinea pig) 100715259, (Mouse) 110310, (Rat) 407757, (Mouse) 77055, (Mouse) 406220, (Rat) 406226, (Rat) 25626, (Guinea pig) 100736243, (Mouse) 16691, (Guinea pig) 100712996, (Guinea pig) 100713272, (Guinea pig) 100713456, (Guinea pig) 100713547, (Guinea pig) 100713966, (Guinea pig) 100732091

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          功能
          receptor activity structural molecule activity protein binding carbohydrate binding protein heterodimerization activity structural constituent of epidermis structural constituent of cytoskeleton keratin filament binding scaffold protein binding MHC class II receptor activity MHC class II protein binding poly(A) RNA binding cadherin binding involved in cell-cell adhesion structural constituent of muscle protein complex binding molecular_function
          参与通路
          epithelial cell differentiation intermediate filament cytoskeleton organization cytoskeleton organization Notch signaling pathway response to estrogen sarcomere organization cell differentiation involved in embryonic placenta development cell cycle anatomical structure morphogenesis viral process tumor necrosis factor-mediated signaling pathway Golgi to plasma membrane CFTR protein transport negative regulation of apoptotic process extrinsic apoptotic signaling pathway hepatocyte apoptotic process cell-cell adhesion positive regulation of epidermis development protein heterotetramerization negative regulation of epithelial cell proliferation aging hair cycle intermediate filament bundle assembly morphogenesis of an epithelium inflammatory response cell proliferation epidermis development keratinocyte differentiation negative regulation of cell migration keratinization innate immune response keratinocyte migration establishment of skin barrier sebaceous gland development biological_process response to radiation tongue morphogenesis cellular response to retinoic acid hemidesmosome assembly intermediate filament-based process cellular response to calcium ion complement activation, lectin pathway negative regulation of inflammatory response response to zinc ion response to ionizing radiation response to hydrostatic pressure response to other organism Wnt signaling pathway wound healing intermediate filament organization hair follicle morphogenesis signal transduction positive regulation of cell growth positive regulation of translation positive regulation of hair follicle development retina homeostasis response to oxidative stress fibrinolysis regulation of angiogenesis mitophagy in response to mitochondrial depolarization embryo development keratinocyte activation keratinocyte proliferation immune system process cell morphogenesis involved in differentiation multicellular organism development
          It has to be done as per old AB suggested Products section.
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