Invitrogen

D2HGDH Polyclonal Antibody

Name: D2HGDH Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-100063

查看其他5个D2HGDH抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (2)

图: 1 / 2

D2HGDH Antibody (PA5-100063) in WB

Western blot analysis of D2HGDH in rat spleen (left lane: treated with blocking peptide). Samples were incubated with D2HGDH polyclonal antibody (Product # PA5-100063).

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Immunogen image

Immunogen Image D2HGDH Polyclonal Antibody

产品信息

PA5-100063

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human D2HGDH(Accession Q8N465), corresponding to amino acid residues E409-P459.

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_2815593

产品详细信息

Antibody detects endogenous levels of total D2HGDH.

靶标信息

This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features.

仅用于科研。不用于诊断过程。未经明确授权不得转售。