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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Reconstitute at 0.5 mg/mL in sterile PBS.
DAB2 mRNA is expressed in normal ovarian epithelial cells but is down-regulated or absent from ovarian carcinoma cell lines. The 770-amino acid predicted protein has an overall 83% identity with the mouse p96 protein, a putative mitogen-responsive phosphoprotein; homology is strongest in the amino-terminal end of the protein in a region corresponding to the phosphotyrosine interaction domain. The down-regulation of DAB2 may play an important role in ovarian carcinogenesis. This gene was initially named DOC2 (for Differentially expressed in Ovarian Cancer) and is distinct from the DOC2A and DOC2B genes (for double C2-like domains, alpha and beta).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Adaptor molecule disabled-2; Differentially expressed in ovarian carcinoma 2; Differentially-expressed protein 2; Disabled homolog 2; DOC-2; FLJ26626
基因别名: DAB2; DOC2
Entrez Gene ID: (Human) 1601