Abnova

DAB2IP Monoclonal Antibody (8C10)

查看其他8个DAB2IP抗体

问题与答案

问题与答案

问题与答案

Additional Information:

{{banner.description}}

{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}

抗体检测数据 (1)

DAB2IP Antibody in Western Blot (WB)

DAB2IP Antibody in Western Blot (WB)

图: 1 / 1

DAB2IP Antibody (H00153090-M04) in WB

DAB2IP monoclonal antibody (M04), clone 8C10. Western Blot analysis of DAB2IP expression in HepG2.

DAB2IP Antibody in Western Blot (WB)

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

Product Image Gallery

DAB2IP Antibody in Western Blot (WB) — DAB2IP monoclonal antibody (M04), clone 8C10. Western Blot analysis of DAB2IP expression in HepG2.

产品信息

H00153090-M04

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

-

酶联免疫吸附实验 (ELISA)

10 µg/mL

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG2a, kappa

分类

Monoclonal

类型

Antibody

克隆号

8C10

抗原

DAB2IP (NP_115941.1, 551 a.a. approximately 650 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

100 µg

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Western Blot (Cell lysate).

Immunogen sequence: KSLSMVDLQD ARTLDGEAGS PAGPDVLPTD GQAAAAQLVA GWPARATPVN LAGLATVRRA GQTPTTPGTS EGAPGRPQLL APLSFQNPVY QMAAGLPLSP

靶标信息

DAB2IP is a Ras GTPase-activating protein (GAP) that acts as a tumor suppressor. The DAB2IP gene is inactivated by methylation in prostate and breast cancers.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: ASK-interacting protein 1; ASK1-interacting protein 1; DAB2 interaction protein; DOC-2/DAB2 interactive protein; MLL fusion partner; nGAP-like protein; RasGAP; unnamed protein product

查看更多收起

基因别名: AF9Q34; AIP-1; AIP1; DIP1/2

查看更多收起

UniProt ID: (Human) Q5VWQ8

查看更多收起

Entrez Gene ID: (Human) 153090

查看更多收起

GTPase activator activity death receptor binding protein binding SH3 domain binding kinase binding protein kinase binding mitogen-activated protein kinase kinase binding mitogen-activated protein kinase kinase kinase binding phosphatidylinositol-3-phosphate binding signaling adaptor activity Toll-like receptor 4 binding phosphatidylinositol 3-kinase regulatory subunit binding identical protein binding protein homodimerization activity vascular endothelial growth factor receptor 2 binding protein serine/threonine kinase activator activity phosphatidylinositol 3-kinase binding macromolecular complex binding cadherin binding protein phosphatase 2A binding phosphatidylinositol-4-phosphate binding 14-3-3 protein binding

negative regulation of transcription from RNA polymerase II promoter negative regulation of cell proliferation extrinsic apoptotic signaling pathway via death domain receptors negative regulation of endothelial cell migration negative regulation of epithelial cell migration negative regulation of epithelial to mesenchymal transition positive regulation of neuron projection development negative regulation of angiogenesis cell motility involved in cerebral cortex radial glia guided migration layer formation in cerebral cortex negative regulation of vascular endothelial growth factor receptor signaling pathway positive regulation of protein complex assembly tumor necrosis factor-mediated signaling pathway negative regulation of toll-like receptor 4 signaling pathway negative regulation of GTPase activity cellular response to unfolded protein tube formation intracellular signal transduction cellular response to vascular endothelial growth factor stimulus vascular endothelial growth factor receptor-2 signaling pathway negative regulation of epidermal growth factor receptor signaling pathway negative regulation of protein catabolic process positive regulation of apoptotic process regulation of GTPase activity regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation of I-kappaB kinase/NF-kappaB signaling regulation of protein complex assembly negative regulation of MAPK cascade positive regulation of MAPK cascade positive regulation of GTPase activity positive regulation of protein catabolic process negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter positive regulation of JNK cascade negative regulation of Ras protein signal transduction negative regulation of fibroblast proliferation neuron projection morphogenesis negative regulation of epithelial cell proliferation regulation of cell cycle negative regulation of protein kinase B signaling intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress negative regulation of G0 to G1 transition negative regulation of ERK1 and ERK2 cascade cellular response to lipopolysaccharide cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to epidermal growth factor stimulus endothelial cell apoptotic process negative regulation of canonical Wnt signaling pathway positive regulation of synapse maturation lipid droplet formation positive regulation of dendrite development regulation of p38MAPK cascade negative regulation of vascular endothelial growth factor signaling pathway negative regulation of NIK/NF-kappaB signaling positive regulation of proteasomal protein catabolic process regulation of intracellular signal transduction positive regulation of IRE1-mediated unfolded protein response positive regulation of neuron migration positive regulation of apoptotic signaling pathway