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          • Primary Antibodies ›
          • DACH2 Antibodies

          Invitrogen

          DACH2 Polyclonal Antibody

          View all (4) DACH2 antibodies

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          Cite DACH2 Polyclonal Antibody

          • Antibody Testing Data (2)
          DACH2 Antibody in Immunohistochemistry (Frozen) (IHC (F))
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          DACH2 Antibody in Immunohistochemistry (Frozen) (IHC (F))
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          DACH2 Antibody (PA5-48072) in IHC (F)

          Immunohistochemical analysis of DACH2 in perfusion fixed frozen sections of mouse embryonic brain (13 d.p.c.). Samples were incubated with DACH2 polyclonal antibody (Product # PA5-48072) using a dilution of 5 µg/mL for 1 hour at room temperature followed by Anti-Goat IgG VisUCyte™ HRP Polymer Antibody. Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was loc... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          DACH2 Antibody in Immunohistochemistry (Frozen) (IHC (F))
          DACH2 Antibody in Western Blot (WB)
          DACH2 Polyclonal Antibody

          Product Details

          PA5-48072

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1 µg/mL
          -

          Immunohistochemistry (Frozen) (IHC (F))

          5-15 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Goat / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          E. coli-derived recombinant human DACH2 Gln419-Gln583
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS with 5% trehalose

          Contains

          No Preservative

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2605976

          Product Specific Information

          This antibody detects endogenous human and mouse DACH2 in Western blots.

          Reconstitute at 0.2 mg/mL in sterile PBS.

          Target Information

          This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: Dach2; Dachshund homolog 2; FLJ31391; MGC138545; RP11-345E19.1

          View more View less

          Gene Aliases: 9430028N04Rik; DACH2

          View more View less

          UniProt ID: (Human) Q96NX9, (Mouse) Q925Q8

          View more View less

          Entrez Gene ID: (Human) 117154, (Mouse) 93837

          View more View less

          Function(s)
          transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly DNA binding winged helix/forkhead transcription factor
          Process(es)
          regulation of transcription, DNA-templated multicellular organism development development of primary female sexual characteristics RNA polymerase II transcriptional preinitiation complex assembly transcription, DNA-templated
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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