Search
Invitrogen
DAGLB Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-26331
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 491-518 amino acids from the central region of human DAGLB
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
200 µg
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Lipase that catalyzes the hydrolysis of arachidonic acid (AA)-esterified diacylglycerols (DAGs) to produce the principal endocannabinoid, 2-arachidonoylglycerol (2-AG) which can be further cleaved by downstream enzymes to release arachidonic acid (AA) for cyclooxygenase (COX)-mediated eicosanoid production (PubMed:14610053). Preferentially hydrolyzes DAGs at the sn-1 position in a calcium-dependent manner and has negligible activity against other lipids including monoacylglycerols and phospholipids (PubMed:14610053). Plays a key role in the regulation of 2-AG and AA pools utilized by COX1/2 to generate lipid mediators of macrophage and microglia inflammatory responses. Functions also as a polyunsaturated fatty acids-specific triacylglycerol lipase in macrophages. Plays an important role to support the metabolic and signaling demands of macrophages. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: DAGL-beta; DGL-beta; Diacylglycerol lipase-beta; PUFA-specific triacylglycerol lipase; Sn1-specific diacylglycerol lipase beta
基因别名: Daglb; E330036I19Rik
UniProt ID: (Mouse) Q91WC9
Entrez Gene ID: (Mouse) 231871
phospholipase activity
prenylcysteine methylesterase activity
lipase activity
hydrolase activity
1-oxa-2-oxocycloheptane lactonase activity
sulfolactone hydrolase activity
3,4-dihydrocoumarin hydrolase activity
butyrolactone hydrolase activity
endosulfan lactone lactonase activity
L-ascorbate 6-phosphate lactonase activity
Ser-tRNA(Thr) hydrolase activity
Ala-tRNA(Pro) hydrolase activity
Cys-tRNA(Pro) hydrolase activity
Ser(Gly)-tRNA(Ala) hydrolase activity
metal ion binding
all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity
retinyl-palmitate esterase activity
mannosyl-oligosaccharide 1,6-alpha-mannosidase activity
mannosyl-oligosaccharide 1,3-alpha-mannosidase activity
methyl indole-3-acetate esterase activity
methyl salicylate esterase activity
methyl jasmonate esterase activity
lipase
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
