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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • DATF1 Antibodies

          Invitrogen

          DATF1 Monoclonal Antibody (734823)

          查看其他9个DATF1抗体

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          Cite DATF1 Monoclonal Antibody (734823)

          • 抗体检测数据 (1)
          DATF1 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          DATF1 Antibody in Western Blot (WB)
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          DATF1 Antibody (MA5-61743) in WB

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          DATF1 Antibody in Western Blot (WB)
          DATF1 Monoclonal Antibody (734823)

          产品信息

          MA5-61743

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          2 µg/mL
          -
          产品规格

          种属反应

          Human

          宿主/亚型

          Mouse / IgG2b

          分类

          Monoclonal

          类型

          Antibody

          克隆号

          734823

          抗原

          E. coli-derived recombinant human DIDO1, Met1-Ser117
          查看免疫原

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Lyophilized

          浓度

          0.5 mg/mL

          纯化类型

          Protein A/G

          保存液

          PBS with trehalose

          内含物

          no preservative

          保存条件

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          运输条件

          Ambient (domestic); Wet ice (international)

          RRID

          AB_3702391

          产品详细信息

          Reconstitute with sterile PBS to a final concentration of 0.5 mg/mL.

          靶标信息

          Dio-1 (Death Inducer-Obliterator-1) is a putative transcription factor that contains two zinc finger motifs. Dio-1 translocates to the nucleus, and activates apoptosis during limb development. Programmed cell death, a highly regulated form of apoptosis, plays an important role in determining the amount of tissue, the shape, and the definition of each digit during limb development. Dio-1 expression is upregulated when an apoptotic signal is detected, and subsequently apoptosis is induced. This process is similar to the expression of NFkB and NGF in response to external signals. Dio-1 expression is suppressed by caspase inhibitors and Bcl-2 expression. This supports the theory that Dio-1 functions in the onset of programmed cell death.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          引用该产品

          生物信息学

          蛋白别名: DATF-1; Death-associated transcription factor 1; Death-inducer obliterator 1; DIO-1

          查看更多 收起

          基因别名: BYE1; C20orf158; DATF-1; DATF1; DIDO1; DIDO2; DIDO3; DIO-1; DIO1; dJ885L7.8; KIAA0333

          查看更多 收起

          UniProt ID: (Human) Q9BTC0

          查看更多 收起

          Entrez Gene ID: (Human) 11083

          查看更多 收起

          功能
          zinc ion binding poly(A) RNA binding general transcription factor
          参与通路
          transcription, DNA-templated apoptotic signaling pathway
          It has to be done as per old AB suggested Products section.
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          性能保障

          只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符,您即可享受免费退换货服务。*

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