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Invitrogen
DAZ3 Polyclonal Antibody
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DAZ3 Antibody (PA5-116174) in IHC (P)
Immunohistochemistry (Paraffin) analysis of DAZ3 in formalin fixed and paraffin embedded human testis tissue using the DAZ3 Polyclonal Antibody (Product # PA5-116174) at a dilution of 1:10-1:50, followed by peroxidase conjugation of the secondary antibody and DAB staining.
产品信息
PA5-116174
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 445-474 amino acids from the C-terminal region of human DAZ3
偶联物
形式
Liquid
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Deleted in azoospermia protein 3
基因别名: DAZ3; pDP1679
UniProt ID: (Human) Q9NR90
Entrez Gene ID: (Human) 57054
