Invitrogen

DBI Polyclonal Antibody

Name: DBI Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-89139

查看其他10个DBI抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (7)

DBI Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 7

DBI Antibody (PA5-89139) in ICC/IF

Immunofluorescence analysis of DBI in NIH/3T3 cells. Samples were incubated with DBI Polyclonal antibody (Product # PA5-89139) using a dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

DBI Antibody in Immunoprecipitation (IP)

Product Image Gallery

产品信息

PA5-89139

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

免疫细胞化学 (ICC/IF)

1:50-1:200

酶联免疫吸附实验 (ELISA)

1 µg/mL

免疫沉淀 (IP)

0.5 µg-4 µg antibody for 200 µg-400 µg whole cells

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein (or fragment)

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.57 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.05% ProClin 300

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2805381

产品详细信息

Immunogen sequence: MWGDLWLLPP ASANPGTGTE AEFEKAAEEV RHLKTKPSDE EMLFIYGHYK QATVGDINTE RPGMLDFTGK AKWDAWNELK GTSKEDAMKA YINKVEELKK KYGI; Positive Samples: HT-29, THP-1, MCF-7, NCI-H460, A673, U-937; Cellular Location: Endoplasmic reticulum, Golgi apparatus

靶标信息

This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: ACBD 1; ACBP; acyl coenzyme A binding protein; acyl-CoA binding protein; Acyl-CoA-binding protein; acyl-Coenzyme A binding domain containing 1; CCK RP; CCKRP; cholecystokinin-releasing peptide, trypsin-sensitive; DBI; Diazepam binding inhibitor (GABA receptor modulator acyl-Coenxyme A binding protein); diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein); Diazepam binding inhibitor (GABA receptor modulator, acyl-Coenxyme A binding protein); diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein); diazepam binding inhibitor, splice form 1b; Diazepam-binding inhibitor; Endozepine; EP; GABA receptor modulator; LRRGT00046; MGC70414; octadecaneuropeptide; triakontatetraneuropeptide; valium

查看更多收起

基因别名: ACBD1; ACBP; Acoabp3; CCK-RP; DBI; endozepine; EP; Odn; RNACOABP3; Ttn

查看更多收起

UniProt ID: (Human) P07108, (Mouse) P31786, (Rat) P11030

查看更多收起

Entrez Gene ID: (Human) 1622, (Mouse) 13167, (Rat) 25045

查看更多收起

功能

lipid binding benzodiazepine receptor binding long-chain fatty acyl-CoA binding protein dimerization activity fatty-acyl-CoA binding protein binding transfer/carrier protein

参与通路