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This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: YVCFFGYPSF KYSHPHHFLK TTAALRGQVV QFKLSDIGEG IREVTVKEWY VKEGDTVSQF DSICEVQSDK ASVTI
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 81%.
The branched-chain alpha-keto acid dehydrogenase complex (BCKD) is an inner-mitochondrial enzyme complex involved in the breakdown of the branched-chain amino acids isoleucine, leucine, and valine. The BCKD complex is thought to be composed of a core of 24 transacylase (E2) subunits, and associated decarboxylase (E1), dehydrogenase (E3), and regulatory subunits. This gene encodes the transacylase (E2) subunit. Mutations in this gene result in maple syrup urine disease, type 2. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 52 kDa mitochondrial autoantigen of primary biliary cirrhosis; BCKAD E2 subunit; BCKAD-E2; BCOADC-E2; Branched chain 2-oxo-acid dehydrogenase complex component E2; branched chain acyltransferase, E2 component; Branched-chain alpha-keto acid dehydrogenase complex component E2; Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex; Dihydrolipoamide branched chain transacylase; dihydrolipoyl transacylase; Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; E2 component of branched chain alpha-keto acid dehydrogenase complex; Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial; lipoamide acyltransferase component of mitochondrial branched-chain alpha-keto acid dehydrogenase complex; MGC9061; mitochondrial branched chain alpha-keto acid dehydrogenase transacylase subunit (E2b)
基因别名: BCATE2; BCKAD-E2; BCKADE2; BCKDHE2; BCOADC-E2; DBT; E2; E2B
UniProt ID: (Human) P11182
Entrez Gene ID: (Human) 1629