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Suggested positive control: human skeletal muscle protein or tissue.
NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up regulates their transcriptional activity, thereby functioning as a nuclear receptor coactivator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer thus indicating a therapeutic intervention. Northern Blot analysis detected a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Androgen receptor complex-associated protein; ARCAP; DDB1 and CUL4 associated factor 6; DDB1- and CUL4-associated factor 6; IQ motif and WD repeat-containing protein 1; IQ motif and WD repeats 1; NRIP; Nuclear receptor interaction protein
基因别名: 1200006M05Rik; ARCAP; DCAF6; IQWD1; MSTP055; NRIP; PC326; RGD1561961
UniProt ID: (Human) Q58WW2, (Mouse) Q9DC22
Entrez Gene ID: (Dog) 480085, (Human) 55827, (Mouse) 74106, (Rat) 289181