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Invitrogen
DCAF6 Polyclonal Antibody
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DCAF6 Antibody (PA5-89724) in WB
Western blot analysis of DCAF6 in extracts of various cell lines. Samples were incubated with DCAF6 Polyclonal antibody (Product # PA5-89724) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-89724
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 460-650 of human IQWD1 (NP_0010179771)
偶联物
形式
Liquid
浓度
1.36 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: DNNNEKLSPK PGTGEPVLSL HYSTEGTTTS TIKLNFTDEW SSIASSSRGI GSHCKSEGQE ESFVPQSSVQ PPEGDSETKA PEESSEDVTK YQEGVSAENP VENHINITQS DKFTAKPLDS NSGERNDLNL DRSCGVPEES ASSEKAKEPE TSDQTSTESA TNENNTNPEP QFQTEATGPS AHEETSTRDS A; Positive Samples: HeLa, LO2; Cellular Location: Nucleus
靶标信息
NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up regulates their transcriptional activity, thereby functioning as a nuclear receptor coactivator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer thus indicating a therapeutic intervention. Northern Blot analysis detected a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Androgen receptor complex-associated protein; ARCAP; DDB1- and CUL4-associated factor 6; IQ motif and WD repeat-containing protein 1; IQ motif and WD repeats 1; NRIP; Nuclear receptor interaction protein
基因别名: 1200006M05Rik; ARCAP; DCAF6; IQWD1; MSTP055; NRIP; PC326
UniProt ID: (Human) Q58WW2
Entrez Gene ID: (Human) 55827
