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Invitrogen
DCLRE1B Polyclonal Antibody
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DCLRE1B Antibody (PA5-93234) in WB
Western blot analysis of DCLRE1B in extracts of THP-1 cells. Samples were incubated with DCLRE1B Polyclonal antibody (Product # PA5-93234) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-93234
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 323-532 of human DCLRE1B (NP_0737471)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.63 mg/mL
规格
63 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: VQQYMSSSSR KPSLLWLLER RLKRPRTQGV VFESPEESAD QSQADRDSKK AKKEKLSPWP ADLEKQPSHH PLRIKKQLFP DLYSKEWNKA VPFCESQKRV TMLTAPLGFS VHLRSTDEEF ISQKTREEIG LGSPLVPMGD DDGGPEATGN QSAWMGHGSP LSHSSKGTPL LATEFRGLAL KYLLTPVNFF QAGYSSRRFD QQVEKYHKPC; Positive Samples: THP-1; Cellular Location: Chromosome, Cytoplasm, Nucleus, centrosome, cytoskeleton, microtubule organizing center, telomere
靶标信息
DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: beta-lactamase DCLRE1B; beta-lactamase MBLAC2; DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae); DNA cross-link repair 1B protein; DNA cross-link repair 1B, PSO2 homolog; PSO2 homolog; SNM1 homolog B; unnamed protein product
基因别名: APOLLO; DKCB8; mSNM1B; SNM1B; SNMIB
UniProt ID: (Human) Q9H816, (Mouse) Q8C7W7
Entrez Gene ID: (Human) 64858, (Mouse) 140917
telomere maintenance
nucleotide-excision repair
double-strand break repair via nonhomologous end joining
telomere maintenance via telomere lengthening
telomere capping
telomeric loop formation
protection from non-homologous end joining at telomere
telomeric 3' overhang formation
interstrand cross-link repair
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
