Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
DDX41 Recombinant Rabbit Monoclonal Antibody (17H29L42)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
图: 1 / 4
DDX41 Antibody (703142) in ICC/IF
For immunofluorescence analysis, MCF-7 cells were fixed and permeabilized using ice cold 100% Acetone for detection of endogenous DDX41 using Anti-DDX41 Recombinant Rabbit Monoclonal Antibody (Product # 703142, 1:100 dilution) and labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034, 1:2000). Panel a) shows representative cells that were stained for detection and localization of DDX41 protein (green), Panel b) is stained for nuclei (blue) using ProLong™ Diamond Antifa... View More
产品信息
703142
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
17H29L42
抗原
Protein corresponding to human DDX41 [aa402-aa569]
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
This antibody is predicted to react with Monkey, Pig, Horse.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
Probable ATP-dependent RNA helicase DDX41 is a DEAD box protein characterized by the conserved motif Asp-Glu-Ala-Asp. It is required during post-transcriptional gene expression and may be involved in pre-mRNA splicing. Mutations affecting the gene can result in myeloproliferative/lymphoproliferative neoplasms, familial (MPLPF).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: 2900024F02Rik; Abstrakt; DEAD (Asp-Glu-Ala-Asp) box polypeptide 41; DEAD box protein 41; DEAD box protein abstrakt homolog; DEAD-box protein abstrakt; Probable ATP-dependent RNA helicase DDX41; putative RNA helicase
基因别名: ABS; DDX41; MPLPF
UniProt ID: (Human) Q9UJV9
Entrez Gene ID: (Human) 51428
mRNA splicing, via spliceosome
apoptotic process
cell proliferation
RNA secondary structure unwinding
cell differentiation
regulation of type I interferon production
positive regulation of type I interferon production
cellular response to interferon-beta
positive regulation of transcription from RNA polymerase II promoter
defense response to virus
