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Invitrogen
DEDD Polyclonal Antibody
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产品信息
PA5-115110
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human DEDD(Accession O75618), corresponding to amino acid residues P138-K188.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total DEDD.
靶标信息
DEDD encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Death effector domain-containing protein; Death effector domain-containing testicular molecule; DEDPro1; FLDED-1; tumor necrosis factor (ligand) superfamily, member 19
基因别名: CASP8IP1; DEDD; DEDD1; DEDPRO1; DEFT; FLDED1; KE05
UniProt ID: (Human) O75618, (Mouse) Q9Z1L3, (Rat) Q9Z2K0
Entrez Gene ID: (Human) 9191, (Mouse) 21945, (Rat) 83631
transcription, DNA-templated
regulation of transcription, DNA-templated
apoptotic process
extrinsic apoptotic signaling pathway via death domain receptors
negative regulation of protein catabolic process
regulation of apoptotic process
decidualization
negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter
spermatogenesis
