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DEK is a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DEK oncogene (DNA binding); Protein DEK
基因别名: D6S231E; DEK
UniProt ID: (Human) P35659
Entrez Gene ID: (Human) 7913
分子生物学功能: chromatin/chromatin-binding, or -regulatory protein