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Invitrogen
DENND4A Polyclonal Antibody
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DENND4A Antibody (PA5-120423) in WB
Western blot analysis of DENND4A in extracts of various cell lines. Samples were incubated with DENND4A Polyclonal antibody (Product # PA5-120423) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-120423
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1500-1650 of human DENND4A (NP_005839.3).
偶联物
形式
Liquid
浓度
3.45 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: HepG2, mouse liver. The target is usually found in the following locations: Nucleus.
Immunogen sequence: RPGRYFLKSS PSTENMHFPS SISSQTRQSC ISTSASGLDT SALSVQGNFD LNSKSKLQEN FCTRSIQIPA NRSKTAMSKC PIFPMARSIS TSGPLDKEDT GRQKLISTGS LPATLQGATD SLGLEWHLPS PDPVTVPYLS PLVVWKELES L
靶标信息
Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. According to PubMed:8056341, it may bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: c-myc promoter binding protein; C-myc promoter-binding protein; DENN domain-containing protein 4A; DENN/MADD domain containing 4A
基因别名: AI115600; AI851943; DENND4A; F730015K02Rik; IRLB; MYCPBP
UniProt ID: (Human) Q7Z401
Entrez Gene ID: (Human) 10260, (Mouse) 102442
