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Invitrogen
DENND4C Polyclonal Antibody
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产品信息
PA5-53279
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: ETNRDYSFPA GLEDHILGEN ISPNTSISGL VPSELTQSNT SLGSSSSSGD VGKLHYPTGE VPFPRGMKGQ DFEKSDHGSS QNTSMSSIYQ NCAMEVLMSS CSQCRACGAL VYDEEIMA
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 89%.
靶标信息
DENND4C is guanine nucleotide exchange factor (GEF) activating RAB10. It promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane in response to insulin.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DENN domain-containing protein 4C; DENN/MADD domain containing 4A pseudogene; DENN/MADD domain containing 4C
基因别名: bA513M16.3; C9orf55; C9orf55B; DENND4C; RAB10GEF
UniProt ID: (Human) A2A3R3
Entrez Gene ID: (Human) 55667
