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Rockland
DEPTOR Polyclonal Antibody
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DEPTOR Antibody (600-401-AV0) in IHC (P)
Immunohistochemistry of Rabbit anti-DEPTOR antibody. Tissue: mouse liver. Primary antibody: DEPTOR antibody at 5 µg/mL. Secondary antibody: Peroxidase rabbit secondary antibody at 1:5,000. Localization: DEPTOR is intracellular. Staining: DEPTOR as precipitated brown signal.
产品信息
600-401-AV0
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Anti-DEPTOR antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid peptide near the internal region of human DEPTOR.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
DEPDC6 is a gene that encodes a protein known for its role in various cellular processes, although the specifics of its function remain not fully elucidated. Located on chromosome 22, DEPDC6 is involved in regulating cell growth and survival by modulating the RAS signaling pathway, a crucial pathway for many cellular functions. Structurally, DEPDC6 contains a DEP domain, which is known to mediate interactions with other proteins that are involved in signal transduction. This domain plays a significant role in facilitating the proper localization and function of the protein. Functionally, DEPDC6 is implicated in controlling the pathways that govern the timing and progression of the cell cycle, highlighting its importance in maintaining cellular homeostasis and preventing uncontrolled cell proliferation. Its dysregulation has been associated with various cancers, emphasizing the need for further studies to fully understand its potential as a therapeutic target.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DEP domain containing 6; DEP domain containing mTOR interacting protein; DEP domain containing MTOR-interacting protein; DEP domain-containing mTOR-interacting protein; DEP domain-containing protein 6; hDEPTOR
基因别名: DEP.6; DEPDC6; DEPTOR; Kiaa4200; RGD1561030
UniProt ID: (Human) Q8TB45, (Mouse) Q570Y9
Entrez Gene ID: (Human) 64798, (Mouse) 97998, (Rat) 314979
