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Recommended positive controls: A431, H1299, HeLa, HepG2, Raji.
Predicted reactivity: Mouse (95%), Rat (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes an enzyme that is a member of the type I subfamily of diacylglycerol kinases, which are involved in lipid metabolism. These enzymes generate phosphatidic acid by catalyzing the phosphorylation of diacylglycerol, a fundamental lipid second messenger that activates numerous proteins, including protein kinase C isoforms, Ras guanyl nucleotide-releasing proteins and some transient receptor potential channels. Diacylglycerol kinase gamma has been implicated in cell cycle regulation and in the negative regulation of macrophage differentiation in leukemia cells. Multiple transcript variants encoding different isoforms have been found for this gene.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DAG kinase gamma; DGK-gamma; Diacylglycerol kinase gamma; diacylglycerol kinase, gamma 90kDa; diacylglyerol kinase gamma; Diglyceride kinase gamma
基因别名: DAGK3; DGK-GAMMA; DGKG
UniProt ID: (Human) P49619
Entrez Gene ID: (Human) 1608
分子生物学功能: kinase