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Invitrogen
DGKZ Monoclonal Antibody (K49027_8F3)
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DGKZ Antibody (MA5-55685) in IHC (P)
Immunohistochemistry analysis of DGKZ in paraffin-embedded cerebellum tissue. Sample was incubated with DGKZ monoclonal antibody (Product # MA5-55685) at a dilution of 5 µg/mL (RT, 1 hour). Antigen was retrieved through addition of boiling Tris/EDTA buffer pH 9 in a pressure cooker for 3 min. Endogenous peroxidase activity was quenched by incubating the sections with 3% H2O2 for 30 min at room temperature. ... View More
产品信息
MA5-55685
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
K49027_8F3
抗原
Recombinant human DGKZ (immunogen range is 832-921).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
RRID
产品详细信息
Sequence of this protein is as follows: STGSKDVVRY LLDHAPPEIL DAVEENGETC LHQAAALGQR TICHYIVEAG ASLMKTDQQG DTPRQRAEKA QDTELAAYLE NRQHYQMIQR
靶标信息
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DAG kinase DAGK6; DAG kinase zeta; DGK-zeta; Diacylglycerol kinase zeta; diacylglycerol kinase, zeta 104kDa; Diglyceride kinase; Diglyceride kinase zeta
基因别名: DAGK5; DAGK6; DGK-ZETA; DGKZ; E130307B02Rik; ENSMUSG00000075035; F730209L11Rik; hDGKzeta; mDGK[z]
UniProt ID: (Human) Q13574, (Mouse) Q80UP3
Entrez Gene ID: (Human) 8525, (Mouse) 104418
protein kinase C-activating G-protein coupled receptor signaling pathway
phosphorylation
cell migration
platelet activation
intracellular signal transduction
mitotic G1 DNA damage checkpoint
negative regulation of catalytic activity
negative regulation of mitotic cell cycle
negative regulation of Ras protein signal transduction
lipid phosphorylation
