Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
DHCR7 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 13
DHCR7 Antibody (PA5-48204) in ICC/IF
Immunocytochemistry analysis of DHCR7 in Hela (Human Cervical epithelial adenocarcinoma cell line) cells. Samples were incubated with DHCR7 polyclonal antibody (Product # PA5-48204) using a dilution of 1:25 followed by Dylight® 488-conjugated goat anti-rabbit IgG at a dilution of 1:200 (green). Cells were 4% paraformaldehyde-fixed, 0. 1% Triton X-100 permeabilized. Immunofluorescence image showing cytoplasm staining on HeLa cell line. Cytoplasmic actin is detected with Dylight® 554 Phalloidin at 1:100 dilution (red). The nuclear counter st... View More
Product Details
PA5-48204
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
C. elegans,
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 437-463 amino acids from the C-terminal region of human DHCR7.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 7-dehydrocholesterol reductase; 7-DHC reductase; delta-7-dehydrocholesterol reductase; Delta7-sterol reductase; putative sterol reductase SR-2; Sterol Delta(7)-reductase; sterol delta-7-reductase; Sterol reductase SR-2
Gene Aliases: AA409147; D7SR; DHCR7; SLOS
UniProt ID: (Human) Q9UBM7, (Mouse) O88455
Entrez Gene ID: (Human) 1717, (Mouse) 13360
blood vessel development
cholesterol biosynthetic process
post-embryonic development
cell differentiation
lung development
cholesterol biosynthetic process via desmosterol
cholesterol biosynthetic process via lathosterol
multicellular organism growth
regulation of cell proliferation
regulation of cholesterol biosynthetic process
oxidation-reduction process
lipid metabolic process
steroid biosynthetic process
steroid metabolic process
cholesterol metabolic process
sterol biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support