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Invitrogen
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Immunogen sequence: EEEEEVTINV TSKAGGIKKY QEYIPVQTGA HADLNPFYQK YSSRTQHAIL YMNPHKINLD LILELLAYLD KSPQFRNIEG AV
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 88%.
DNA helicase and probable main scaffold component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; according to PubMed:20687897 the contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Recruited by YY1 to YY1-activated genes, where it acts as an essential coactivator. Binds DNA. In vitro, has double-stranded DNA-dependent ATPase activity. Involved in UV-damage excision repair, DNA replication and chromosome segregation during normal cell division cycle.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ATP-dependent RNA helicase DHX29; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 29; DEAH (Asp-Glu-Ala-His) box polypeptide 29; DEAH box protein 29; Nucleic acid helicase DDXx
基因别名: DDX29; DHX29
UniProt ID: (Human) Q7Z478
Entrez Gene ID: (Human) 54505