Search Thermo Fisher Scientific
图: 1 / 3
Positive Control: 293T, A431, HeLa, HepG2
Predicted reactivity: Mouse (82%), Rat (80%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure. DHX36 (DEAH box protein 36), also known as MLE-like protein 1 and RNA helicase associated with AU-rich element ARE (RHAU), belongs to RNA helicase of the DEAH family and may function in sex development and spermatogenesis. It is expressed in testis and is evolutionary conserved with true orthologs in almost all animal species. DHX36 plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. DHX36 is required for early embryogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Asp-Glu-Ala-His; ATP-dependent DNA/RNA helicase DHX36; ATP-dependent RNA helicase DHX36; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 36; DEAD/H box polypeptide 36; DEAH (Asp-Glu-Ala-His) box polypeptide 36; DEAH box protein 36; DEAH-box protein 36; G4 resolvase-1; G4-resolvase 1; G4-resolvase-1; G4R1; MLE-like protein 1; probable ATP-dependent RNA helicase DHX36; RNA helicase associated with AU-rich element ARE; RNA helicase associated with AU-rich element protein
基因别名: 2810407E23Rik; AI452301; AU022184; DDX36; DHX36; G4R1; KIAA1488; mKIAA1488; MLEL1; RHAU
UniProt ID: (Human) Q9H2U1, (Rat) D4A2Z8, (Mouse) Q8VHK9
Entrez Gene ID: (Human) 170506, (Rat) 310461, (Mouse) 72162