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This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
Immunogen sequence: PDGSLSQAAM MQSALAKERR ELKQAQREAE MDSIPMGLNK HWVDPLPDAE GRQIAANMRG IGMMPNDIPE WKKHAFGGNK ASYGKKTQMS ILEQRESLP
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
This gene is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ATP-dependent RNA helicase DHX8; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 8 (RNA helicase); DEAH (Asp-Glu-Ala-His) box polypeptide 8; DEAH box protein 8; RNA helicase HRH1
基因别名: DDX8; DHX8; HRH1; PRP22; PRPF22
UniProt ID: (Human) Q14562
Entrez Gene ID: (Human) 1659
分子生物学功能: RNA helicase