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Invitrogen
DIAPH1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-21409
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human DIAPH1. The exact sequence is proprietary.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.69 mg/mL
Amount
69 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: A431, H1299, HeLa, HepG2, Molt-4, Raji.
Predicted reactivity: Mouse (95%), Rat (94%), Pig (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: diaphanous 1; diaphanous-1; Diaphanous-related formin-1; DRF1; FLJ25265; mammalian diaphanous related formin 1; p140DIA; Protein diaphanous homolog 1; similar to Drosophila diaphanous; unnamed protein product
Gene Aliases: DFNA1; DIA1; DIAP1; DIAPH1; DRF1; hDIA1; LFHL1; mDia1; SCBMS
Entrez Gene ID: (Human) 1729
cytoskeleton organization
brain development
sensory perception of sound
actin cytoskeleton organization
actin filament polymerization
neuron projection development
regulation of microtubule-based process
protein localization to microtubule
synaptic vesicle endocytosis
regulation of release of sequestered calcium ion into cytosol
regulation of cytoskeleton organization
cellular response to histamine
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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