Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-65243
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2663361
产品详细信息
Immunogen sequence: KSESIITQSEE KADFVIIPAE GIENRTEGTD SPLSRDWRPG SPGTYLETSW EEQLLEQQEY LEKEMEEAKK MISGLQALLL NGSLPEDEQE RPLALCEPGV NP
Highest antigen sequence identity to the following orthologs - mouse 89%, rat 92%.
靶标信息
This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Coiled-coil protein DIX1; Coiled-coil-DIX1; DIX domain-containing protein 1; Dixin
基因别名: CCD1; DIXDC1; KIAA1735
UniProt ID: (Human) Q155Q3
Entrez Gene ID: (Human) 85458
cell cycle
cerebral cortex radially oriented cell migration
forebrain ventricular zone progenitor cell division
regulation of actin cytoskeleton organization
negative regulation of neuron differentiation
canonical Wnt signaling pathway
regulation of microtubule cytoskeleton organization
positive regulation of canonical Wnt signaling pathway
