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Antibody detects endogenous levels of total DKK2.
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: dickkopf 2; dickkopf 2 homolog; Dickkopf gene 2; dickkopf homolog 1; dickkopf homolog 2; dickkopf homolog 4; dickkopf related protein-2; Dickkopf-2; Dickkopf-related protein 2; dkk-2; hDkk-2; mDkk-2
基因别名: DKK-2; DKK2; Dkk4; UNQ682/PRO1316
UniProt ID: (Human) Q9UBU2, (Mouse) Q9QYZ8
Entrez Gene ID: (Human) 27123, (Mouse) 56811, (Rat) 295445