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Invitrogen
DLL1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-47207
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant human DLL1 Ser22-Gly540
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.2 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody detects recombinant human DLL1 in direct ELISAs. In direct ELISAs, less than 1% cross-reactivity with recombinant human DLL4 and recombinant mouse DLL4 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
Delta-like protein 1 (DLL1) is a transmembrane protein characterized by epidermal growth factor (EGF)-like repeats. It is a ligand for Notch receptor. It blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: delta-like ligand 1; drosophila Delta homolog 1; epididymis secretory sperm binding protein; H-Delta-1; Notch ligand; OTTHUMP00000017690; unnamed protein product
基因别名: Delta; DELTA1; DL1; NEDBAS
UniProt ID: (Human) O00548
Entrez Gene ID: (Human) 28514
cell fate determination
somitogenesis
heart looping
marginal zone B cell differentiation
type B pancreatic cell development
cell communication
Notch signaling pathway
determination of left/right symmetry
regulation of blood pressure
positive regulation of cell proliferation
negative regulation of cell proliferation
proximal/distal pattern formation
positive regulation of gene expression
astrocyte development
regulation of somitogenesis
spinal cord development
cerebellar molecular layer formation
cerebellar Purkinje cell layer structural organization
hemopoiesis
cell differentiation
regulation of cell adhesion
negative regulation of epithelial cell differentiation
regulation of vascular endothelial growth factor receptor signaling pathway
negative regulation of interleukin-10 production
negative regulation of glial cell apoptotic process
organ growth
regulation of growth
negative regulation of cell differentiation
negative regulation of epidermal cell differentiation
negative regulation of myoblast differentiation
negative regulation of neuron differentiation
negative regulation of Notch signaling pathway
positive regulation of Notch signaling pathway
positive regulation of endocytosis
positive regulation of transcription from RNA polymerase II promoter
lateral inhibition
skeletal muscle tissue growth
regulation of skeletal muscle tissue growth
positive regulation of skeletal muscle tissue growth
neuron fate specification
regulation of neurogenesis
regulation of cell division
retina development in camera-type eye
retina morphogenesis in camera-type eye
Notch signaling pathway involved in arterial endothelial cell fate commitment
left/right axis specification
nephron development
proximal tubule development
loop of Henle development
clathrin-mediated endocytosis
energy homeostasis
endothelial tip cell fate specification
neuronal stem cell population maintenance
skin epidermis development
regulation of vascular endothelial growth factor signaling pathway
positive regulation of sprouting angiogenesis
negative regulation of cardiac muscle cell differentiation
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