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Invitrogen
DLX2 Recombinant Rabbit Monoclonal Antibody (PSH13-47)
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DLX2 Antibody (MA570006) in IHC (P)
Immunohistochemistry analysis of DLX2 in paraffin-embedded mouse embryo tissue. Samples were incubated with DLX2 monoclonal antibody (Product # MA570006) using a dilution of 1:40,000 for 1 hour at room temperature. The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0) for 20 minutes. The tissues were blocked in 1% BSA for 20 minutes at room temperature, washed with... View More
产品信息
MA570006
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
PSH13-47
抗原
Recombinant protein within human DLX2 aa 1-328.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4, with 0.1% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Positive control: Mouse brain tissue, mouse embryo tissue, rat brain tissue, rat embryo tissue.
Subcellular location: Nucleus.
靶标信息
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DII A; DLX-5; homeobox Dlx5; Homeobox protein DLX-2; Homeobox protein TES-1
基因别名: AW121999; Dlx-2; Dlx2; Dlx5; Tes-1; Tes1
UniProt ID: (Mouse) P40764
Entrez Gene ID: (Mouse) 13392, (Rat) 296499
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
single-stranded RNA binding
protein binding
sequence-specific DNA binding
homeodomain transcription factor
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
multicellular organism development
proximal/distal pattern formation
subpallium development
hippocampus development
olfactory bulb development
forebrain neuron differentiation
regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment
cerebral cortex GABAergic interneuron differentiation
cerebral cortex GABAergic interneuron fate commitment
cell differentiation
odontogenesis of dentin-containing tooth
negative regulation of Notch signaling pathway
positive regulation of transcription from RNA polymerase II promoter
embryonic cranial skeleton morphogenesis
embryonic skeletal system development
negative regulation of oligodendrocyte differentiation
branching morphogenesis of a nerve
cartilage development
