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Invitrogen
DMRTA2 Polyclonal Antibody
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DMRTA2 Antibody (PA5-35234) in ICC/IF
Immunocytochemistry analysis of DMRTA2 in U251 cells. Samples were incubated with DMRTA2 polyclonal antibody (Product # PA5-35234) using a dilution of 1:25 for 1 h at 37°C followed by Alexa Fluor® 488 conjugated donkey anti-rabbit at a dilution of 1:400 for 50 min at 37°C. Cells were fixed with 4% PFA (20 min) and permeabilized with Triton X-100 (0.1%, 10 min). Cytoplasmic actin was counterstained with Alexa Fluor® 555 (red) conjugated Phalloidin (7 units/mL, 1 h at 37°C). Nuclei were counterstained with DAPI (blue) (10 µg/mL, 10 min). DMR... View More
产品信息
PA5-35234
产品规格
种属反应
Human,
Mouse,
Zebrafish
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 487-515 amino acids from the C-terminal region of human DMRTA2
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is predicted to react with bovine based on sequence homology.
靶标信息
DMRTA2 may be involved in sexual development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DMRT-like family A2; DMRT5; doublesex and mab-3 related transcription factor like family A2; Doublesex- and mab-3-related transcription factor 5; Doublesex- and mab-3-related transcription factor A2
基因别名: DMRT5; DMRTA2
UniProt ID: (Human) Q96SC8, (Mouse) A2A9A2
Entrez Gene ID: (Human) 63950, (Mouse) 242620, (Zebrafish) 474350
core promoter proximal region sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
protein homodimerization activity
metal ion binding
protein heterodimerization activity
DNA binding
sequence-specific DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
DNA-binding transcription factor
positive regulation of neuroblast proliferation
regulation of transcription, DNA-templated
brain development
sex differentiation
cerebral cortex regionalization
skeletal muscle cell differentiation
neuron fate specification
dopaminergic neuron differentiation
regulation of transcription from RNA polymerase II promoter
telencephalon development
corticotropin hormone secreting cell differentiation
