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Invitrogen
DNA2 Polyclonal Antibody
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DNA2 Antibody (PA5-118398) in IHC (P)
Immunohistochemistry (Paraffin) analysis of DNA2 in paraffin-embedded rat large intestine tissue. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with DNA2 polyclonal Antibody (Product # PA5-118398) at a dilution of 1:400 for ... View More
产品信息
PA5-118398
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide within human DNA2 aa 960-1000
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
TBS, pH 7.4, with 50% glycerol, 0.2% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
DNA2 is a conserved helicase/nuclease involved in themaintenance of mitochondrial and nuclear DNA stability.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DNA replication ATP-dependent helicase-like homolog; DNA replication ATP-dependent helicase/nuclease DNA2; DNA replication helicase 2 homolog; DNA2-like helicase; hDNA2
基因别名: DNA2; DNA2L; E130315B21Rik; hDNA2; KIAA0083
UniProt ID: (Human) P51530, (Mouse) Q6ZQJ5
Entrez Gene ID: (Human) 1763, (Mouse) 327762
DNA binding
DNA helicase activity
helicase activity
nuclease activity
protein binding
ATP binding
ATPase activity
site-specific endodeoxyribonuclease activity, specific for altered base
5'-flap endonuclease activity
5'-3' DNA helicase activity
single-stranded DNA-dependent ATPase activity
metal ion binding
4 iron, 4 sulfur cluster binding
nucleotide binding
catalytic activity
endonuclease activity
hydrolase activity
phosphoric ester hydrolase activity
T/G mismatch-specific endonuclease activity
retroviral 3' processing activity
iron-sulfur cluster binding
DNA replication checkpoint
DNA double-strand break processing
DNA replication
mitochondrial DNA replication
DNA repair
base-excision repair
cellular response to DNA damage stimulus
metabolic process
DNA duplex unwinding
DNA replication, Okazaki fragment processing
DNA replication, removal of RNA primer
mitochondrial DNA repair
positive regulation of DNA replication
nucleic acid phosphodiester bond hydrolysis
telomere maintenance via recombination
telomere maintenance
DNA synthesis involved in DNA repair
strand displacement
regulation of signal transduction by p53 class mediator
mitotic telomere maintenance via semi-conservative replication
