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Invitrogen
DOG-1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-78778
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence at the C-terminus of human TMEM16A (927-943aa KVLMVELFMREEQDKQQ).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
500 µg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Liver Tissue, Rat Skeletal Muscle Tissue.
靶标信息
DOG-1, the novel marker, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of kit or PDGFR alpha mutation status.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Ano1; anoctamin 1, calcium activated chloride channel; AT5G45830; ATDOG1; Ca2+-activated Cl- channel; cacium activated chloride channel; calcium activated chloride channel; DELAY OF GERMINATION 1; discovered on gastrointestinal stromal tumors protein 1; FLJ10261; GAAS5; germination ability after storage 5; GLUCOSE SENSING QTL 5; GSQ5; K15I22.3; K15I22_3; membrane protein; oral cancer overexpressed 2; transmembrane protein 16A; transmembrane protein 16A (eight membrane-spanning domains); tumor-amplified and overexpressed sequence 2; unnamed protein product
基因别名: DOG1; INDMS; MYMY7; ORAOV2; TAOS2; TMEM16A
UniProt ID: (Human) Q5XXA6, (Mouse) Q8BHY3
Entrez Gene ID: (Human) 55107, (Mouse) 101772, (Rat) 309135
receptor binding
calcium activated cation channel activity
intracellular calcium activated chloride channel activity
voltage-gated chloride channel activity
chloride channel activity
protein binding
iodide transmembrane transporter activity
identical protein binding
protein homodimerization activity
protein dimerization activity
chloride transport
phospholipase C-activating G-protein coupled receptor signaling pathway
iodide transport
cellular response to heat
regulation of membrane potential
detection of temperature stimulus involved in sensory perception of pain
detection of mechanical stimulus involved in sensory perception of pain
trachea development
mucus secretion
protein localization to membrane
cation transmembrane transport
glial cell projection elongation
cellular response to peptide
chloride transmembrane transport
ion transmembrane transport
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
