Search
Invitrogen
DOG-1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 2
DOG-1 Antibody (PA5-80338) in ICC/IF
Immunofluorescence staining of ANO1 in HeLa cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with DOG-1 Polyclonal Antibody (Product # PA5-80338, 1:1,000) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to cytoplasm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-80338
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to the C-terminus of the Human Ano1
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human Ano1.
靶标信息
DOG-1, the novel marker, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of kit or PDGFR alpha mutation status.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Ano1; anoctamin 1, calcium activated chloride channel; AT5G45830; ATDOG1; Ca2+-activated Cl- channel; cacium activated chloride channel; calcium activated chloride channel; DELAY OF GERMINATION 1; discovered on gastrointestinal stromal tumors protein 1; FLJ10261; GAAS5; germination ability after storage 5; GLUCOSE SENSING QTL 5; GSQ5; K15I22.3; K15I22_3; membrane protein; oral cancer overexpressed 2; transmembrane protein 16A (eight membrane-spanning domains); tumor-amplified and overexpressed sequence 2; unnamed protein product
基因别名: DOG1; INDMS; MYMY7; ORAOV2; TAOS2; TMEM16A
UniProt ID: (Human) Q5XXA6
Entrez Gene ID: (Human) 55107
receptor binding
calcium activated cation channel activity
intracellular calcium activated chloride channel activity
voltage-gated chloride channel activity
chloride channel activity
protein binding
iodide transmembrane transporter activity
identical protein binding
protein homodimerization activity
protein dimerization activity
chloride transport
phospholipase C-activating G-protein coupled receptor signaling pathway
iodide transport
ion transmembrane transport
cellular response to heat
detection of temperature stimulus involved in sensory perception of pain
trachea development
mucus secretion
protein localization to membrane
cation transmembrane transport
glial cell projection elongation
cellular response to peptide
chloride transmembrane transport
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
