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The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 from CML cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Docking protein 2; docking protein 2, 56kD; docking protein 2, 56kDa; Dok-R; Dok-related protein; Downstream of tyrosine kinase 2; FRIP; IL-Four Receptor Interacting Protein; IL-four receptor-interacting protein; p56 dok-2; p56(dok-2)
基因别名: Dok-2; DOK2; DokR; Frip; p56DOK; p56dok-2
UniProt ID: (Human) O60496, (Mouse) O70469
Entrez Gene ID: (Dog) 486133, (Human) 9046, (Rat) 290361, (Mouse) 13449