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Invitrogen
DPCR1 Polyclonal Antibody
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Product Details
PA5-43536
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the C-terminal of human DPCR1 (aa 383-432).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: SHLNKTEVTH QVPTGSFTLI TSRTKLSSIT SEATGNESHP YLNKDGSQKG
Sequence homology: Human: 100%
Target Information
The DPCR1 gene, known as diffuse panbronchiolitis critical region 1, encodes a protein involved in immune responses and epithelial cell function, particularly in the respiratory system. Although the specific functions of DPCR1 are not extensively characterized, the gene is located within a region linked to diffuse panbronchiolitis, a chronic inflammatory lung disease. DPCR1 is thought to contribute to immune regulation, potentially influencing innate immune responses and epithelial cell interactions critical for maintaining respiratory health. Its expression in airway epithelial cells suggests a role in modulating mucus production, barrier integrity, and protection against pathogens. Aberrant expression of DPCR1 may impact respiratory function, contributing to conditions such as asthma or chronic obstructive pulmonary disease (COPD) by affecting immune responses and inflammation. Understanding DPCR1's functions and regulatory mechanisms in the respiratory system is essential for exploring its potential as a therapeutic target for respiratory diseases characterized by chronic inflammation and immune dysregulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bCX105N19.6; Diffuse panbronchiolitis critical region protein 1; MGC126710; MGC126712; Mucin-like protein 3
Gene Aliases: C6orf37; DPCR1; MUCL3; PBLT
UniProt ID: (Human) Q3MIW9
Entrez Gene ID: (Human) 135656
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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