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Abnova
DPH5 Polyclonal Antibody, MaxPab™
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DPH5 Antibody (H00051611-B01P) in WB
Western Blot analysis of DPH5 expression in transfected 293T cell line (H00051611-T01) by DPH5 MaxPab polyclonal antibody.
Lane 1: DPH5 transfected lysate(31.35 KDa).
Lane 2: Non-transfected lysate.
Lane 1: DPH5 transfected lysate(31.35 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00051611-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
DPH5 (NP_001070862.1, 1 a.a. approximately 285 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MLYLIGLGLG DAKDITVKGL EVVRRCSRVY LEAYTSVLTV GKEALEEFYG RKLVVADREE VEQEADNILK DADISDVAFL VVGDPFGATT HSDLVLRATK LGIPYRVIHN ASIMNAVGCC GLQLYKFGET VSIVFWTDTW RPESFFDKVK KNRQNGMHTL CLLDIKVKEQ SLENLIKGRK IYEPPRYMSV NQAAQQLLEI VQNQRIRGEE PAVTEETLCV GLARVGADDQ KIAAGTLRQM CTVDLGEPLH SLIITGGSIH PMEMEMLSLF SIPENSSESQ SINGL
靶标信息
This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Diphthamide biosynthesis methyltransferase; Diphthine methyl ester synthase; diphthine synthase; DPH5 homolog; protein x 0011
基因别名: AD-018; CGI-30; DPH5; HSPC143; NPD015
UniProt ID: (Human) Q9H2P9
Entrez Gene ID: (Human) 51611
