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Invitrogen
DPH5 Polyclonal Antibody
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产品信息
PA5-61242
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: SVNQAAQQLL EIVQNQRIRG EEPAVTEETL CVGLARVGAD DQKIAAGTLR QMCTVDLGEP LHSLIITGGS IHPMEMEMLS LFSIPENSSE SQSING
Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 79%.
靶标信息
This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Diphthamide biosynthesis methyltransferase; Diphthine methyl ester synthase; diphthine synthase; DPH5 homolog; protein x 0011
基因别名: AD-018; CGI-30; DPH5; HSPC143; NPD015
UniProt ID: (Human) Q9H2P9
Entrez Gene ID: (Human) 51611
