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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: SLEVSRSPRR SRRELEVRSP RQNKYSVLLP TYNERENLPL IVWLLVKSFS ESGINYEIII IDDGSPDGTR DVAEQLEKIY GSD
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 81%.
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Dolichol-phosphate mannose synthase subunit 1; Dolichol-phosphate mannosyltransferase subunit 1; Dolichyl-phosphate beta-D-mannosyltransferase subunit 1; DPM synthase subunit 1; Mannose-P-dolichol synthase subunit 1; MPD synthase subunit 1; OTTMUSP00000017164; RP23-391M18.1
基因别名: DPM1
Entrez Gene ID: (Human) 8813