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Invitrogen
DPPA2 Monoclonal Antibody (210CT5.14.6.1)
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产品信息
MA5-37519
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
210CT5.14.6.1
抗原
DPPA2 recombinant protein
偶联物
形式
Liquid
纯化类型
Protein G
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
The DPPA2 (Developmental Pluripotency Associated 2) gene is prominently expressed in embryonic stem cells and is critical for maintaining their pluripotency and self-renewal capabilities. Located on chromosome 3, DPPA2 belongs to a family of genes that play significant roles in early embryonic development and epigenetic remodeling. The expression of DPPA2 is tightly regulated through mechanisms such as DNA methylation, and it is involved in regulatory pathways that control the expression of core pluripotency factors. Beyond its role in stem cell biology, DPPA2 expression is also noted in various cancers, where it can become reactivated, suggesting its involvement in oncogenic processes. In the context of cancer, DPPA2, along with DPPA4, has been studied for its potential to facilitate cellular reprogramming and contribute to tumorigenesis. Given its expression pattern, DPPA2 serves as both a marker of pluripotent potential in stem cells and a potential target for cancer diagnostics and therapy due to its reactivation in malignant tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cancer/testis antigen 100; Developmental pluripotency-associated protein 2; ECSA; embryonic stem cell (ESC) associated transcript 15-2; Pluripotent embryonic stem cell-related gene 1 protein
基因别名: CT100; DPPA2; ECAT15-2; PESCRG1
UniProt ID: (Human) Q7Z7J5
Entrez Gene ID: (Human) 151871
