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Abnova
DPPA4 Polyclonal Antibody, MaxPab™
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产品信息
H00055211-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
DPPA4 (AAH32846.1, 1 a.a. approximately 294 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MEKAKGKEWT STEKSREEDQ QASNQPNSIA LPGTSAKRTK EKMSVKGSKV LCPKKKAEHT DNPRPQKKIP IPPLPSKLPP VNLIHRDILR AWCQQLKLSS KGQKLDAYKR LCAFAYPNQK DFPSTAKEAK IRKSLQKKLK VEKGETSLQS SETHPPEVAL PPVGEPPALE NSTALLEGVN TVVVTTSAPE ALLASWARIS ARARTPEAVE SPQEASGVRW CVVHGKSLPA DTDGWVHLQF HAGQAWVPEK QEGRVSALFL LPASNFPPPH LEDNMLCPKC VHRNKVLIKS LQWE
靶标信息
The DPPA4 gene encodes developmental pluripotency associated 4, a protein that plays a crucial role in maintaining stem cell pluripotency and facilitating early embryonic development. DPPA4 is primarily expressed in pluripotent stem cells, such as embryonic stem cells, where it contributes to the regulation of gene expression and chromatin structure necessary for pluripotency and differentiation. This protein is also involved in the establishment of epigenetic marks that influence developmental pathways, ensuring the proper formation of tissue types during embryogenesis. DPPA4 functions in stem cell renewal and differentiation, impacting cellular processes that are fundamental to early development. Beyond its roles in normal physiology, DPPA4 has been studied in the context of oncology, where its expression is often upregulated in certain cancers, indicating its potential as a biomarker for tumorigenic stem cell-like properties. Research continues to explore DPPA4's mechanisms and interactions to understand its contributions to development and its implications in disease states, particularly in cancer biology and regenerative medicine.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Developmental pluripotency-associated protein 4
基因别名: 2410091M23Rik; DPPA4
UniProt ID: (Human) Q7L190
Entrez Gene ID: (Human) 55211
