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Invitrogen
DPYD Polyclonal Antibody
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产品信息
PA5-106882
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human DPYD(Accession Q12882), corresponding to amino acid residues L775-T825.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total DPYD.
靶标信息
Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DHPDHase; Dihydropyrimidine dehydrogenase [NADP(+)]; Dihydrothymine dehydrogenase; Dihydrouracil dehydrogenase; DPD
基因别名: AI315208; DHP; DHPDHASE; DPD; DPYD; E330028L06Rik
UniProt ID: (Human) Q12882, (Rat) O89000, (Mouse) Q8CHR6
Entrez Gene ID: (Human) 1806, (Rat) 81656, (Mouse) 99586
protein binding
dihydropyrimidine dehydrogenase (NADP+) activity
protein homodimerization activity
metal ion binding
flavin adenine dinucleotide binding
NADP binding
4 iron, 4 sulfur cluster binding
uracil binding
dihydroorotate dehydrogenase activity
iron-sulfur cluster binding
nucleotide binding
catalytic activity
oxidoreductase activity
oxidoreductase activity, acting on the CH-CH group of donors
dehydrogenase
oxidoreductase
metabolite interconversion enzyme
purine nucleobase catabolic process
pyrimidine nucleobase catabolic process
thymine catabolic process
uracil catabolic process
thymidine catabolic process
beta-alanine biosynthetic process
pyrimidine nucleoside catabolic process
oxidation-reduction process
UMP biosynthetic process
response to nutrient
circadian rhythm
uracil metabolic process
response to drug
response to glucocorticoid
