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Recommended positive controls: Raji, K562, NCI-H929.
Predicted reactivity: Mouse (91%), Rat (92%), Xenopus laevis (91%), Pig (94%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine. Also involved the degradation of the chemotherapeutic drug 5-fluorouracil.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DHPDHase; Dihydropyrimidine dehydrogenase [NADP(+)]; Dihydrothymine dehydrogenase; Dihydrouracil dehydrogenase
基因别名: DHP; DHPDHASE; DPD; DPYD
UniProt ID: (Human) Q12882
Entrez Gene ID: (Human) 1806
分子生物学功能: dehydrogenase oxidoreductase metabolite interconversion enzyme