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Invitrogen
DPYSL3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-100454
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human DPYSL3(Accession Q14195), corresponding to amino acid residues G497-E547.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total CRMP4.
Target Information
DPYSL3 is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. DPYSL3 plays a role in axon guidance, neuronal growth cone collapse and cell migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Collapsin response mediator protein 4; collapsin response mediator protein 4 long; CRMP-4; Dihydropyrimidinase-related protein 3; DRP-3; LCRMP-4; testicular secretory protein Li 7; TOAD-64/Ulip/CRMP; TOAD-64/Ulip/CRMP protein 4b; tuc-4; TUC-4b; ULIP-1; Unc-33-like phosphoprotein 1; unnamed protein product
Gene Aliases: CRMP-4; CRMP4; DPYSL3; DRP-3; DRP3; LCRMP; TUC-4b; TUC4; ULIP; ULIP-1; ULIP1
UniProt ID: (Human) Q14195, (Mouse) Q62188, (Rat) Q62952
Entrez Gene ID: (Human) 1809, (Mouse) 22240, (Rat) 25418
dihydropyrimidinase activity
protein binding
hydrolase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SH3 domain binding
filamin binding
chondroitin sulfate binding
identical protein binding
phosphoprotein binding
hydrolase
pyrimidine nucleobase catabolic process
nervous system development
positive regulation of neuron projection development
negative regulation of neuron projection development
negative regulation of cell migration
neuron development
response to axon injury
actin filament bundle assembly
positive regulation of filopodium assembly
actin crosslink formation
cellular response to cytokine stimulus
protein homooligomerization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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