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Invitrogen
DPYSL3 Polyclonal Antibody
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DPYSL3 Antibody (PA5-116546) in WB
Western blot analysis of DPYSL3 in extracts of various cell lines. Samples were incubated with DPYSL3 Polyclonal antibody (Product # PA5-116546) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3 min.
产品信息
PA5-116546
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 440-520 of human DPYSL3 (NP_0013781)
偶联物
形式
Liquid
浓度
0.6 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: Mouse brain, Rat brain
Immunogen sequence: RGAPLVVICQ GKIMLEDGNL HVTQGAGRFI PCSPFSDYVY KRIKARRKMA DLHAVPRGMY DGPVFDLTTT PKGGTPAGSA R
靶标信息
DPYSL3 is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. DPYSL3 plays a role in axon guidance, neuronal growth cone collapse and cell migration.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Collapsin response mediator protein 4; CRMP-4; Dihydropyrimidinase-related protein 3; DRP-3; TOAD-64/Ulip/CRMP; TOAD-64/Ulip/CRMP protein 4b; tuc-4; TUC-4b; ULIP-1; Unc-33-like phosphoprotein 1
基因别名: CRMP-4; Crmp4; Dpysl3; DRP-3; Drp3; TUC-4b; TUC4; Ulip; ULIP-1; Ulip1
UniProt ID: (Mouse) Q62188, (Rat) Q62952
Entrez Gene ID: (Mouse) 22240, (Rat) 25418
nervous system development
positive regulation of neuron projection development
negative regulation of neuron projection development
negative regulation of cell migration
actin filament bundle assembly
protein homooligomerization
positive regulation of filopodium assembly
actin crosslink formation
pyrimidine nucleobase catabolic process
neuron development
response to axon injury
cellular response to cytokine stimulus
