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Invitrogen
DPYSL3 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-52760
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
规格
10 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: IIDHVVPEPE SSLTEAYEKW REWADGKSCC DYALHVDITH WNDSVKQEVQ NLIKDKGVNS FMVYMAYKDL YQVSNTELYE IFTCLGELGA IAQVHAENGD IIAQEQTRML EMGITGPE
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.
靶标信息
DPYSL3 is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. DPYSL3 plays a role in axon guidance, neuronal growth cone collapse and cell migration.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: collapsin response mediator protein 4 long; LCRMP-4; testicular secretory protein Li 7; tuc-4; unc-33-like phosphoprotein 1; unnamed protein product
基因别名: CRMP-4; CRMP4; DRP-3; DRP3; LCRMP; ULIP; ULIP-1
UniProt ID: (Human) Q14195
Entrez Gene ID: (Human) 1809
dihydropyrimidinase activity
protein binding
hydrolase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SH3 domain binding
filamin binding
chondroitin sulfate binding
identical protein binding
phosphoprotein binding
pyrimidine nucleobase catabolic process
positive regulation of neuron projection development
negative regulation of neuron projection development
negative regulation of cell migration
neuron development
response to axon injury
actin filament bundle assembly
positive regulation of filopodium assembly
actin crosslink formation
cellular response to cytokine stimulus
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