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Invitrogen
DST Polyclonal Antibody
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图: 1 / 4
DST Antibody (PA5-106906) in ICC/IF
Immunofluorescent analysis of DST in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and DST polyclonal antibody (Product # PA5-106906) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-106906
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human DST(Accession Q03001), corresponding to amino acid residues V7423-T7473.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total DST.
靶标信息
As basal cells of stratified squamous epithelia begin to migrate in response to wound healing, they lose their cell-substrate adhesion junctions, the hemidesmosomes. The hemidesmosome is an adhesion structure of the epidermal-dermal junction in keratinocytes. When keratinocytes migrate laterally or upward to differentiate they must control the formation and disintegration of the hemidesmosomes. The bullous pemphigoid antigen BPAG1 is a hemidesmosomal protein of the cutaneous basement membrane zone. The primary sequence deduced from full-length human cDNAs predicts that this molecule consists of a central rod region and flanking globular domains. A neuronal isoform, BPAG1n3 is the result of differential splicing of BPAG1. BPAG1n3 is distinguished by its initial 32 amino acid residues and by the absence of the amino-terminal half of the actin-binding domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 230 kDa bullous pemphigoid antigen; 230/240 kDa bullous pemphigoid antigen; BPA; Bullous pemphigoid antigen 1; bullous pemphigoid antigen 1, isoform 5; bullous pemphigoid antigen 1, isoforms 1/2/3/4; bullous pemphigoid antigen 1, isoforms 6/7; Dystonia musculorum protein; Dystonin; Hemidesmosomal plaque protein; Microtubule actin cross-linking factor 2
基因别名: 2310001O04Rik; A830042E19Rik; ah; athetoid; AW554249; BP230; BP240; Bpag; BPAG1; BPAG1-n; DMH; DST; DT; KIAA0728; Macf2; mKIAA0728; nmf203; nmf339
UniProt ID: (Mouse) Q91ZU6
Entrez Gene ID: (Mouse) 13518, (Rat) 316313
cytoskeleton organization
cell cycle arrest
cell adhesion
axonogenesis
retrograde axonal transport
regulation of microtubule polymerization or depolymerization
cytoplasmic microtubule organization
intracellular transport
microtubule cytoskeleton organization
response to wounding
maintenance of cell polarity
hemidesmosome assembly
intermediate filament cytoskeleton organization
cell motility
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
