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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MIEDSGKRGN TMAERRQLFA EMRAQDLDRI RLSTYRTACK LRFVQKKCNL HLVDIWNVIE ALRENALNNL DPNTELNVSR LEAVLSTIFY QLNKRMPTTH QIHVEQSISL LLNFLLAAFD PEGHGKISVF AVKMALATLC GGKIMDKLRY IFSMISDSSG VMVYGRYDQF LREVLKLPTA VFEGPSFGYT EQSARSCFSQ QKKVTLNGFL DTLMSDPPPQ CLVWLPLLHR LANVENVFHP VECSYCHSES MMGFRYRCQQ CHNYQLCQDC FWRGHAGGSH SNQHQMKEYT SWKSPAKKLT NALSKSLSCA SSREPLHPMF PDQPEKPLNL AHIVDTWPPR PVTSMNDTLF SHSVPSSGSP FITRSMLESS NRLDEEHRLI ARYAARLAAE SSSSQPPQQR SAPDISFTID ANKQQRQLIA ELENKNREIL QEIQRLRLEH EQASQPTPEK AQQNPTLLAE LRLLRQRKDE LEQRMSALQE SRRELMVQLE GLMKLLKTQG AGSPRSSPSH TISRPIPMPI RSASACSTPT HTPQDSLTGV GGDVQEAFAQ SSRRNLRNDL LVAADSITNT MSSLVKELNS EVGSETESNV DSEFARTQFE DLVPSPTSEK AFLAQIHARK PGYIHSGATT STMRGDMVTE DADPYVQPED ENYENDSVRQ LENELQMEEY LKQKLQDEAY QVSLQG
The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Alpha-dystrobrevin; DTN-A; Dystrobrevin alpha; dystrobrevin, alpha; Dystrophin-related protein 3
基因别名: D18S892E; DRP3; DTN; DTN-A; DTNA; LVNC1
UniProt ID: (Human) Q9Y4J8
Entrez Gene ID: (Human) 1837